
A team of professionals behind world-class innovation

Director
Dr. Mariko Hirata
Dr. Mariko Hirata built her clinical foundation through extensive experience at university and general hospitals, before dedicating many years to aesthetic surgery and dermatology. She possesses exceptional expertise in injectable treatments such as hyaluronic acid and botulinum toxin, achieving natural and refined results.
At Tokyo Relife Clinic, she integrates advanced regenerative medicine with aesthetic medicine, providing cutting-edge treatments that pursue beauty and youth. Her practice is dedicated to maximizing each patient’s individual appeal, while ensuring both safety and effectiveness.
2011 Graduated from the Faculty of Medicine, Saga University
2011 Kyushu University Hospital
2012 National Hospital Organization Kyushu Medical Center
2013 Major Aesthetic Surgery Clinic
2014 Director, Major Aesthetic Surgery Clinic
2019 Dermatology Clinic (insurance-based practice)
2020 Aesthetic Surgery and Dermatology Clinics in Tokyo
2025 Director, Tokyo Relife Clinic
Certifications
Allergan Juvéderm Vista Certification
Allergan Botox Vista Certification

Chief Advisor [Regenerative Medicine]
Dr. Tsuyoshi Takato
After graduating from the University of Tokyo School of Medicine, he received his M.D. from the same school. He has gained extensive experience at domestic and international medical institutions. He specializes in oral and plastic surgery. Formerly Professor of Oral and Maxillofacial Surgery at the University of Tokyo Graduate School of Medicine, Department of Surgery, Division of Sensory and Motor Functional Medicine. Formerly, Director of Tissue Engineering Department, The University of Tokyo Hospital. Former Director of the 22nd Century Medical Center at the same hospital (concurrent post). Currently Director of JR Tokyo General Hospital. Director of the Department of Dental Surgery and Plastic and Reconstructive Surgery. Director of the Japanese Society for Regenerative Medicine. He has introduced clinical experience and techniques from Canada and the U.S. to Japan, and has developed many new techniques himself. He has been active for many years as a specialist in plastic and cosmetic surgery. In recent years, he has focused on research and clinical application of regenerative medicine, which has received high acclaim both in Japan and abroad. He has served as Vice President of the Japanese Society for Regenerative Medicine. He received the Achievement Award from the Japanese Society for Regenerative Medicine.
Graduated from the University of Tokyo, School of Medicine
1979 Formation of a surgical department at Tokyo University Medical Center
1981 Formation Surgery, Tokyo University School of Medicine Hospital
1989 Lecturer, Department of Plastic and Reconstructive Surgery, University of Tokyo Hospital, University of Tokyo Health Administration Center
1992 Assistant Professor of Oral Surgery, University of Tokyo
1996 Professor and Chief of Department of Oral and Maxillofacial Surgery, Dentistry and Orthodontics
1997 Professor, Department of Sensory and Motor Functional Medicine, Division of Surgery, Graduate School of Medicine, The University of Tokyo
Chief, Department of Oral and Maxillofacial Surgery and Orthodontics, The University of Tokyo Hospital
2001 Director, Department of Tissue Engineering, The University of Tokyo Hospital (concurrent position)
2011 Director, 22nd Century Medical Center, The University of Tokyo Hospital (concurrent position)
2017 Professor Emeritus, University of Tokyo; Director, JR Tokyo General Hospital
2022 Director, Nihon University
2023 Director Emeritus, JR Tokyo General Hospital; Visiting Professor, Tokyo Medical University

Chief Advisor [Aesthetic Medicine].
Dr. Nobutaka Furuyama
He is a pioneer in the field of cosmetic surgery, having started the practice in earnest at university hospitals in Japan and leading the industry. He specializes in "non-scalpel rejuvenation treatment," and is internationally recognized for his Botox, hyaluronic acid injections, and thread treatments for sagging skin, and contributes to the development of aesthetic medicine in Japan and abroad as head faculty of injections.
Graduated from Kitasato University School of Medicine
1981 Joined the Department of Plastic and Reconstructive Surgery, Kitasato University School of Medicine
1985 Chief Resident
1987 Research Fellow, Department of Plastic and Reconstructive Surgery, Kitasato University, M.D. [Morphological evaluation of cultured skin models using collagen thin films].
1988 Lecturer, Department of Plastic and Reconstructive Surgery, Kitasato University
1995 Established Jiyugaoka Clinic
2019 Part-time Lecturer, Department of Plastic and Reconstructive Surgery, Chiba University School of Medicine
Jiyugaoka Clinic, chaired by Dr. Furuyama, is our group clinic.

Dr. Koichi Yoshimi
After graduating from the Faculty of Medicine at Nagasaki University, Dr. Yoshimi trained in plastic surgery at Keio University Hospital. He subsequently gained extensive clinical experience in aesthetic surgery, dermatology, laser therapy, and plastic surgery. He has served as the director of major aesthetic surgery clinics, including Otsuka Aesthetic Plastic Surgery, and has long been at the forefront of Japan’s aesthetic medicine field.
He is a member of the Japan Society of Plastic and Reconstructive Surgery, the Japanese Dermatological Association, and the Japan Society for Laser Surgery and Medicine, as well as the Japan Society for Regenerative Medicine and the Japanese Society for Extracellular Vesicles. With his wealth of experience and proven skills, Dr. Yoshimi is dedicated to providing safe, effective, and individually tailored aesthetic medical treatments.
1990 Graduated from the Faculty of Medicine, Nagasaki University
1990 Department of Plastic Surgery, Keio University Hospital
1991 Major Aesthetic Surgery Clinic
1997 Director, Otsuka Aesthetic Plastic Surgery, Subsequently served as director at multiple aesthetic surgery clinics
2025 Appointed Aesthetic Medicine Physician, Tokyo Relife Clinic
Memberships
Japan Society of Plastic and Reconstructive Surgery
Japanese Dermatological Association
Japan Society for Laser Surgery and Medicine
Japan Society for Regenerative Medicine (General Incorporated Association)
Japanese Society for Extracellular Vesicles

Director, Center for Cell Innovation Research and Regenerative Therapy [M.D.].
Dr. Marlen Doskali
In his home country of Kazakhstan, he is a liver surgeon and is also active in transplantation surgery. He has over 15 years of expertise and technical background in cellular immunotherapy and development of innovative therapies. He is currently the Director of the Center for Cell Innovation Research and Regenerative Therapy at Tokyo ReLife Clinic, where he oversees two important divisions: the Cell Processing Center Division and the Cell Innovation Research Division. He is an outstanding leader in the field of regenerative medicine and cell research and leads the team.

Director, Cell Innovation Research Division [Clinical Laboratory Technician, M.D.].
Dr. Yoshiyasu Shinohara
He has over 20 years of experience in cell biology, genetic testing, and regenerative medicine in academia, life science companies, and biotech companies. In addition, he is also involved in the development of new therapeutic technologies. In addition, he leads research that pushes the boundaries of cell science worldwide, while brushing up therapeutic technologies.
◎ Successfully led projects to develop therapies based on adipose-derived stem cells, umbilical cord-derived mesenchymal stem cells, and fibroblasts.
◎ Selected by AMED (Japan Agency for Medical Research and Development) for a project to promote innovation in medical-engineering collaboration, and promoted innovative projects as Principal Investigator and Project Leader.
◎ Published numerous papers in journals and contributed to the advancement of liver diseases, oncology, and regenerative medicine.
◎ Promoted research on autophagy inhibitors for cancer therapy and new therapeutic and diagnostic methods for liver diseases.

Associate Professor (Special Appointment), Graduate School of Science, The University of Tokyo
Mr. Hiroyuki Matsumura
Dr. Matsumura is a specially appointed associate professor in the Department of Chemistry, Graduate School of Science, The University of Tokyo, and a member of the Goda Laboratory. The Goda Lab integrates quantum science, nanotechnology, microfluidics, data science, and other fields to develop new tools in cytometry and optical science. By utilizing these technologies, the lab aims to discover unknown phenomena, elucidate mechanisms, and develop applications in science, industry, and medicine. Members of the Goda Lab, including Dr. Matsumura, have received numerous awards from academic societies, foundations, and government agencies, and Dr. Matsumura continues to be an active contributor to the team’s research.

Founder, Chief Executive Officer
Yoshiaki Furuyama
Yoshiaki Furuya is a healthcare entrepreneur who leads Tokyo Relife Clinic, specializing in regenerative medicine and longevity science. Born in Tokyo in 1984, he began his career in aesthetic medical management at Jiyugaoka Clinic, before shifting his focus to the clinical application of regenerative therapies.
Currently, he promotes advanced treatments such as stem cell therapy, exosome therapy, and senolytics (drugs for the elimination of senescent cells), aiming to control aging processes and extend healthy life expectancy. He is also actively involved in clinical research in collaboration with universities and research institutions, while expanding international medical tourism and treatment programs for high-net-worth patients. His guiding principle is the promotion of “evidence-based longevity medicine that patients can trust.”
CEO, Tokyo Relife Group
COO, Jiyugaoka Clinic Group
Founder, Endowed Chair of “Cellular Senescence Control,” Graduate School of Science, The University of Tokyo
Executive Director, Jiyugaoka Academy (NPO)
Board Member, Jiyugaoka Station Central Association
Lecturer, Sanno University
Research Fellow, Graduate School of Science, The University of Tokyo (since 2025)